CIB- RHR Gene Editing and Mouse Models Assessment Core (GEMMA core)

The CIB-RHR Gene Editing and Mouse Models Assessment (GEMMA) Core provides specialized expertise and infrastructure focused on generation, characterization, and assessment of gene-edited and mutant mouse models. Under Dr. Gunn’s leadership, the GEMMA Core builds on a long-standing research program in mouse models of disease and molecular mechanisms underlying neurodevelopment and neurodegeneration.

The breadth of these projects underscores the GEMMA Core’s relevance to investigators studying neurodevelopmental disorders, neurodegeneration, peripheral neuropathies, developmental heart defects and other conditions amenable to mouse genetic modeling. Beyond model generation, the GEMMA Core’s remit includes rigorous phenotypic assessment and characterization, leveraging the researchers backgrounds in molecular genetics, developmental biology and neuropathology. The core functions within the Center for Integrated Biomedical and Rural Health Research’s broader infrastructure for research, advisory boards and administrative support, aligning with the McLaughlin Research Institute’s mission to advance biomedical science.